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Sequence-Based Genotyping

Looking for a technology for simultaneously discovery and scoring of genetic markers without genome sequence information in a cost-effective way? Use KeyGene’s Sequence-Based Genotyping! KeyGene licenses Sequence-Based Genotyping methods for commercial and research purposes. If you are interested in a tailor-made licensing proposal contact our expert Wendeline Ubing, Licensing Counsel.

Our current licensees include:

Commercial in-house use:
– Bayer Crop Science. Read more: Press release January 11, 2016
– Enza Zaden
– Rijk Zwaan
– Limagrain Vegetables Seeds
– Takii & Co. Ltd.
– One global seed company

 Licensed Service Providers:
– IGA Technology Services. Read more: Press release June 19, 2014
– Floragenex Inc. Read more: Press release July 28, 2015
– LGC. Read more: Press release January 11, 2016
– University of Minnesota Genomics Center. Read more: Press release January 16, 2017
– University Wisconsin-Madison, Biotechnology Center. Read more: Press release January 15, 2018

Academic Internal Research:
Are you a non-profit research organization and want to access KeyGene’s Sequence-Based Genotyping technology for internal research purposes in a quick and easy way? Download the form, fill in the required details and return the form to our expert. After payment of the licensing fee you will obtain the license. There is a licensing form for US and RoW non-profit research organizations.

Licensing form nonprofit research organizations US: Licensing form US
Licensing form nonprofit research organizations RoW: Licensing form RoW

Our current licensees include:

Licensees Europe:
– The James Hutton Institute
– University of Hohenheim
– University of Zürich
– Forschungszentrum Jülich
– Wageningen University
– ETH Zürich
– CNAG-CRG, Barcelona
– University of Liverpool
– WSL Swiss Federal Research Institute
– Aberystwyth University
– Julius Kühn-Institut
– University of Edinburgh

Licensees United States:
– University of Minnesota Genomics Center
– South Dakota State University
– Oregon State University
– Tennessee Technological University
– Samuel Roberts Noble Foundation
– San Diego Zoo Global
– North Carolina State University
– University of Delaware
– Kansas State University
– Virginia Tech
– University of North Carolina at Chapel Hill

KeyGene’s SBG technology is protected by a global dominant patent portfolio (more information in this press release). This portfolio with granted and pending patents protects methods known as SBG, GBS, two-enzyme GBS, tunable GBS, RAD, ddRAD, 2b-RAD, SLAF-seq and related methods using restriction enzyme digestion and/or amplicon sequencing to produce complexity-reduced genome fractions sequenced with next-generation sequencing platforms.

Applications of KeyGene’s SBG technology in plants using tunable levels of complexity reduction have been published by Truong and co-workers (PLoS ONE, e37565, 2012) reporting double restriction enzyme digestion in Arabidopsis thaliana and triple digestion in lettuce. Van Poecke and co-workers (Plant Biotechnology Journal, 2013) published the use of SBG in durum wheat using double digestion in combination with a +2 selective primer to fine-tune the preferred level of complexity reduction.

KeyGene® SNPSelect

For details and forms to obtain a license to use the KeyGene® SNPSelect technology, please contact our expert for more information.