A gene controlling a trait of interest can be located in proximity to a gene that has a negative influence on product quality. With the use of several AFLP® markers in this region, individuals with recombinant haplotypes can be selected to remove this linkage drag.
Its value
AFLP® based removal of linkage drag:
is a cost effective way to find recombinants;
allows clear visualization of genotype connected to the locus (locus haplotyping);
forms ideal starting material for backcross conversion or breeding;
provides detailed knowledge regarding the genetic location of genes controlling the trait;
is especially interesting for recessive traits;
is also possible for QTLs;
allows the introduction of new characteristics into breeding germplasm.
Example
A dramatic illustration of the power of KeyGene's linkage drag removal capabilities was the introduction of aphid (Nasanovia) resistant lettuce (see poster below). The resistance originates from a wild relative of lettuce but the trait could previously not be exploited because it was linked to early senescence.
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