Scroll down

We are enthusiastic about our breakthrough technology innovations. Through licensing, KeyGene aims to provide its partners access to its IP that can help to create competitive advantages for our partners.
Our technologies and trait components are accessible to breeding companies, academic organizations,  as well as commercial service providers. For non-profit research organizations, favorable conditions for access apply.

Many global seed companies including Bayer, Enza Zaden, Rijk Zwaan, Limagrain Vegetable Seeds and Takii & Co. Ltd have one or more licenses for our technologies. KeyGene’s technologies also find application outside Agrofood, such as in cancer diagnostics.

Our innovations

Pollen viability

Improve fertility and viability in interspecific hyrbids, using compounds that inhibit the MRN-ATM pathway.

Parthenogenesis promotor

Promoter sequences that convert a sexual allele into a parthenogenesis allele, which is capable of inducing parthenogenesis.

Coregeneration of recalcitrant plants

Regenerate recalcitrant plant cells into regenerative shoots by establishing contact to regenerative plant cells.

Msi2 gene for DH induction

Mutant Musashi RNA-binding protein 2 (Msi2) proteins, nucleic acid sequences, and plants for haploid inducer lines.

CENPC Gene for DH induction

Mutant Centromere Protein C proteins, nucleic acid sequences, and plants for haploid inducer lines.

Parthenogenesis gene

A gene(fragment) capable of converting parthenogenesis to plants.

Diplospory gene

A gene(fragment) capable of converting diplospory to a plant

Efficient plant selection

Plant selection based on genotypical and/or phenotypical data sets and deep learning.

Target enrichment through selective sequencing

A combination of TarSeq and subsequent selective sequencing, a highly effective method for target sequence enrichment.

Covalently closing DNA strands by TelN for NGS library preparation

TelN adapters / primers for NGS library preparation for amplification free enrichment of target sequences.

Improving drought resistance: pectinesterase

For plants with increased drought resistance by impairing the expression of functional pectinesterase.

Semi-solid state for nucleic acid handling

For methods and kits for HMW nucleic acid library preparation, effectively reducing shear stress.

Targeted Sequence Addition

Method to increase shoot regeneration by overexpressing genes for histidine kinases

Shoot regeneration by CHK genes

Method to increase shoot regeneration by overexpressing genes for histidine kinases

Dual guide for CRISPR editing of plant cells

Effective genome editing CRISPR system nuclease guided by non-covalently linked, crRNA and tracrRNA

Genes for hormone free regeneration

Transient expression of 2 genes circumvents the need for cytokinin and auxin

Germacrene A Synthase mutants

Decreased sesquiterpene lactones and increased levels of squalene & phenolic compounds

Mad7 for genome editing in plant cells

Highly effective Type V CRISPR system for plant cell genome editing

Genome editing for altered protein function

Editing of a coding sequence by two site-specific nucleases that causes a frameshift

Genome editing by programmed deaminases

Genome editing using cysteine or adenine deaminase fused to a site-specific nuclease e.g. a CAS

Plant genome editing by Cpf1

Genome editing of plant protoplasts for high mutagenesis frequencies

Glycerol-free transfection of CRISPR complex

Glycerol free genome editing of protoplasts using CRISPR-CAS protein and in vitro transcribed gRNA

Targeted translocation

Translocation between 2 homologous/homeologous chromosomes via double-strand break and rejoining

Oligonucleotide-delivery to protoplasts

Method to effectively deliver mutagenic nucleobases to plant protoplasts using polyethylene glycol

Improved seed germination

Seeds with improved germination quality, by pollination of graft hybrid mother plants.

2S1 Graft hybrid technology

Plants with improved epidermis-based complex traits, e.g. biotic stress resistance

Virtual reality greenhouse

3D visualization of individual plants and association with plant characteristic data

Improving Drought Resistance in Plants: UPL3

Plants with increased drought resistance by impairing the expression of functional UPL3

Improving drought resistance in plants: UPL4

Plants with increased drought resistance by impairing the expression of functional UPL4

Genotyping polyploids using molecular tags

Effective genotyping of polyploids using probes comprising unique molecular indices

Accurately amplifying mixtures of probes

Production of oligonucleotides, in particular targeting oligonucleotides or nucleic acid probes.

SNPSelect

Genotyping, based upon locus & allele identifiers; a way to amplify and process DNA into probes

Directed genomic selection

Genomic selection using genome-wide complementarity, taking into account recombination probabilities

Targeted Sequencing

Using gRNA-CAS complexes to selectively sequence target regions

CropPedia

Interactive genomics data management and visualization system

Combinatorial barcodes

At least two nucleotide sequence barcodes, for identifying sample origin in NGS.

KeyPoint® Breeding

Multiplex detection of variation of genes / loci of interest, based on high throughput sequencing.

Sequence based genotyping (SBG, GBS)

Genotyping SNP, SSR and indel polymorphisms in a single streamlined process for multiple samples.