Precision Breeding

By inducing mutations in functionally validated genes, for example by Genome Editing, the Precision Breeding platform delivers levels of trait expression beyond the existing range of phenotypic expression. This enables IP protection and delivers (pre) breeding material or even true to type varieties with one superior trait. Creating crops with improved traits such as reproduction traits, biotic and abiotic stress, via high precision genome editing.

KeyGene uses protoplast systems for several precision breeding technologies. This results in non-GM plants.

* CRISPR/Cas9

* KeyBase XL®

Breeding is all about combining genetic diversity available in worldwide germplasm to produce crop varieties with superior qualities. However, natural genetic variation in available germplasm of food crops is limited and will soon become insufficient to address the great food security challenge of producing enough food to feed a growing world population. Plant breeders are therefore continuously searching for new sources of genetic variation, and are increasingly interested in novel technologies allowing for the creation of such variation. KeyBase® is such a technology. KeyBase® permits the the creation of novel single point mutations at pre-defined positions in the genome of the crop of interest by means of the introduction of short oligonucleotides. However minute, such changes can have tremendous advantages for the crop and can result in yield increase, drought tolerance, insect resistance or increased sugar content, just to name a few. Imagine drought resistant corn growing in arid regions of Africa… That is what we are aiming at with KeyBase®.

* Base editing (targeted)

* KeyPoint® Mutation breeding for random and selected mutations

Picture this: a breeder has bred a tomato variety. Great taste and very juicy. A valuable product of years of patient crossing and selection. Difficult to improve. But in some aspects less than ideal: a bit too tall, shelf life not optimal. Here is where breeding at the gene level comes in: individual genes that control such less-than-ideal aspects can be altered in a non-GMO way and selected for improvement. The result is a precisely enhanced product that maintains the overall so appreciated qualities of the original variety.